GH Axis Peptides

Growth hormone secretagogues and related peptides influence the somatotropic axis with implications for reproductive biology and cellular repair.

Growth Hormone Modulation

Peptides like GHRP-2, GHRP-6, Ipamorelin and CJC-1295 stimulate endogenous GH release. Growth hormone has documented roles in ovarian folliculogenesis, oocyte quality and testicular function.

Ovarian Environment

GH receptors are present in granulosa cells and oocytes. Research suggests GH co-treatment may improve outcomes in poor responders undergoing IVF, though evidence remains heterogeneous.

Male Reproductive Function

The GH-IGF-1 axis influences Sertoli and Leydig cell function. Optimising this axis may support spermatogenesis and testosterone production in select cases.

Research Areas

  • Poor ovarian response and GH co-stimulation

  • Age-related decline in oocyte quality

  • Recovery and cellular repair mechanisms

  • Metabolic context and IGF-1 signalling

Research note: GH axis peptides are largely investigational for fertility applications. Clinical use requires appropriate medical supervision and regulatory compliance.